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However, it is critical to recognize that clinical symptoms of deficiency can manifest without anemia or low serum vitamin B12 levels
Health Canada has not approved either peptide for therapeutic use, which is typical for compounds still in clinical development
Neurological symptoms often develop gradually and may appear before anaemia is detected on blood tests
Vitamin B12 is the most chemically complex of all the vitamins, and cyanocobalamin and hydroxycobalamin are synthetically derived therapeutic forms of vitamin B12.6 Hydroxycobalamin protein binding capacity is greater than that of cyanocobalamin and both of them may cause allergic reactions.6 Vitamin B12 may lead to allergic reactions because of its cobalt molecule, molecular complexity or high molecular mass
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